Re: Vit A Update--Dana
- Subject: Re: Vit A Update--Dana
- Date: Tue, 04 Nov 2003 19:46:53 -0000
- Yahoo! Message Number: 96659
- Onibasu Link: http://onibasu.com/archives/am/96659.html
Here is the post from another board, where Dr. McCandless talked
about the dosages.--Tod
Listmates: As you know, in the exploratory study Dr. Vojdani and I
recently conducted on 32 ASD children, 14 showed elevated salivary
rubeola IgA levels, and 5 were at 5+. These levels correlated well
with elevation of IgG rubeola antibody levels, but we did not have
this test on all the kids in the salivary study. We are going to
repeat the study more rigorously, this time using both the saliva for
the secretory IgG and the serum for IgG antibodies.
At the DAN!, Dr. Sidney Baker spoke of a study showing that 200,000
iu of Vitamin A was not enough to ameliorate the impact of measles
infection - the children needed 400,000 iu for two days (800,000 iu
total). As I have said, if the rubeola IgA salivary titers are
elevated (per our study), IgG levels are very elevated, the child has
a history of strong reaction to MMR and/or followed by regression
soon thereafter, and certainly with brain antibodies indicating
autoimmune reaction, I believe there is indication they may benefit
from this large dose, followed by 10,000 to 25,000 per day per age
and size. Some parents are reporting benefit from even smaller
doses, as I was originally suggesting 250,000 iu 1st day, then
200,000, then 150,000 etc. with maintenance at 10,000 to 25,000
(subtracting the up to 5000 in CLO, with the rest in fish oil A or
vit A palmitate.
What kind to use? Fish oil vit. A vs vit. A palmitate? Dr. Pangborn
has given me the following information - "Per the Merck Index, the
palmitate form of all-trans or retinol is the preponderant ester in
fish liver oils (cod, shark). But I do not like synthetic vit A
palmitate unless one has to use pharmacologic doses such as Sid
(Baker) is describing. ------ Synthetic palmitate can be a problem
in allergicaly sensitive individuals. ----- Natural fish oil
includes all-trans-retinol, -ci-retinol, and probably some very
similar molecules. There's no guarantee that a synthetic palmitate
will have these. -----I'm wary of synthetics, but again, for >200,000
iu doses one may have to use what's practical. (This is item 10150
("Vitamin A") in the Merck index.
To be practical in solid or powder supplements, one finds vit A
acetate. Some potency is lost in the acetate form, about 15%.
Under 5000 iu, there's no reason to test serum retinol levels.
Actually, tests are not reliable anyway. The most important thing is
to watch for symptoms of A overdose: headache, nausea, dry scaly
skin, vertigo, blurred vision and erythema or rash. Serum calcium
will be elevated, as hypervitaminosis A features hypercalcemia."
For those who did not participate in the original exploratory study,
and who believe they can get saliva samples from their children, you
may want to participate in our upcoming study. This time we will
obtain serum IgG rubeola antibodies and 4 small (1cc) samples of
saliva throughout a 24 hour period. Though this is more trouble, it
might be easier to get 1 cc at a time, as some moms could not manage
to get 5cc at once, which is what we were requiring in the first
study.
My original interest in doing this study was to try to ascertain what
child might be a candidate for the high vitamin A dose, but clearly
it stands as a less invasive way of trying to find out if our kids
have active measles in their guts (less invasive than a scope). For
those who are interested in participating in this study, please post
me a brief note about your child's reaction or aftermath of the MMR.
Thanks! Jaquelyn McCandless
-- In Autism-Mercury@yahoogroups.com, "grapenutsgirl" <ams1088>
wrote:
-Could someone please direct me to the message number or date that<tod_s_2000>
Dr. McC posted the protocol for high dose vitamin A?
Thanks,
Sheryl
-- In Autism-Mercury@yahoogroups.com, "tod_s_2000"
wrote:
Dana--I am considering the high A for my daughter, because hercurrently
measles titers are very high. She is 32 pounds, age 3, and
gets 20,000 iu per day, which has really helped. Are there anysigns
I should look for when I try this? Will she act differently forthe
two days?<danasview>
--- In Autism-Mercury@yahoogroups.com, "danasview"
wrote:the
--- In Autism-Mercury@yahoogroups.com, Mum231ASD wrote:
Theres a key here somewhere for Sam...........finding it is
since Iproblem,bigger
chelation is long term though after 44 rounds we are seeing
stuff nowetc -
particularly in self confidence, awareness, receptive, calmer
AT LAST. Bugs
are under control, no yeast flares now for ages, actually
stopped goingthere.
after it LOL - could we be close to the 'Dana stage'????
I remember major improvements around round 50, so maybe you are
Dana
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